Deep Brain Stimulation of Thalamic Nuclei for Treatment of Intractable Epilepsy
نویسندگان
چکیده
1Department of Physiology, Paramedical Sciences Faculty, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran 2Electrophysiology Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, IR Iran 3Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, IR Iran 4Department of Neurophysiology, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran 5Department of Physiology, Isfahan University of Medical Sciences, Isfahan, IR Iran 6Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, IR Iran
منابع مشابه
Rapid Eye Movement Sleep: A Predictive Marker of Success and Efficacy of Deep Brain Stimulation in Intractable Epilepsy
Deep brain stimulation (DBS) is progressively establishing as an alternative therapy in various neurological disorders not amenable satisfactorily to medication. In IE also, DBS of anterior thalamic nucleus (ATNDBS) has been approved by FDA and several studies have reported its success and efficacy including the randomized SANTE trials [1]. As is common with any therapeutic strategy, ATNDBS als...
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OBJECTIVE Deep brain stimulation (DBS) of the centromedian thalamic nucleus (CM) can be an alternative treatment option for intractable epilepsy patients. Since CM may be involved in widespread cortico-subcortical networks, identification of the cortical sub-networks specific to the target stimuli may provide further understanding on the underlying mechanisms of CM DBS. Several brain structures...
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OBJECTIVES Experimental data and case reports of intractable epilepsy patients treated with deep brain stimulation (DBS) of the internal nuclei suggest a considerable anticonvulsant effect. We intended to describe the results of DBS on subthalamic nuclei and anterior thalamic nuclei (STN and ATN) from our patients and to evaluate the long-term efficiency and safety of DBS for controlling intrac...
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INTRODUCTION The cognitive and behavioral effect of deep brain stimulation (DBS) administered to the deep cerebral nuclei for epilepsy treatment is unknown. We investigated the cognitive outcomes at least 12 months after DBS to the bilateral anterior thalamic nucleus (ATN) for controlling intractable epilepsy. METHODS Nine patients with intractable epilepsy who were not candidates for resecti...
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Epilepsy is the most common neurological disease with no definitive method in treatment. Notably, the main way to treat and control epileptic seizures is drug therapy. However, about 20-30% of patients with epilepsy are drug resistant and require other therapeutic manners. Deep brain stimulation is a new therapeutic strategy for these patients. Conspicuously, there are no clear answers for basi...
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